BDBM352474 US9809545, 4Bp

SMILES Cc1cncc(c1)-c1cnc([nH]1)[C@H](Cc1ccc(F)cc1)n1ccc(cc1=O)-c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=ZHFSFCWOGFEINE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352474   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM352474(US9809545, 4Bp)
Affinity DataKi:  54nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
Go to US Patent