BDBM3544 4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-triamine::CHEMBL92937::PD153035 Analog 44

SMILES CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N

InChI Key InChIKey=WUWMKQIRTKOCMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3544   

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3544(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-tr...)
Affinity DataIC50:  0.692nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3544(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,6,7-tr...)
Affinity DataIC50:  0.690nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed