BDBM355706 1-(2-{(2S,4R)-4-Fluoro-2-[(1R,2S)- 2-(2-fluoro-phenyl)- cyclopropylcarbamoyl]-pyrrolidin- 1-yl}-2-oxo-ethyl)-5-methyl-1H- pyrazolo[3,4-c]pyridine-3- carboxylic acid amide::US9815819, 71

SMILES Cc1cc2c(nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)N[C@@H]3C[C@H]3c3ccccc3F)c2cn1)C(N)=O

InChI Key InChIKey=OSMVBGFWMJKWDJ-MWLKLMTCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355706   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355706(1-(2-{(2S,4R)-4-Fluoro-2-[(1R,2S)- 2-(2-fluoro-phe...)
Affinity DataIC50:  90nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent