BDBM355707 1-(2-{(2S,4R)-2-[(1R,2S)-2-(4- Chloro-phenyl)- cyclopropylcarbamoyl]-4-fluoro- pyrrolidin-1-yl}-2-oxo-ethyl)-1H- pyrazolo[3,4-c]pyridine-3- carboxylic acid amide::US9815819, 72

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)N[C@@H]2C[C@H]2c2ccc(Cl)cc2)c2cnccc12

InChI Key InChIKey=NXDAAWAJWFCSTJ-SPUZQDLCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355707   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355707(1-(2-{(2S,4R)-2-[(1R,2S)-2-(4- Chloro-phenyl)- cyc...)
Affinity DataIC50:  309nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent