BDBM355717 1-{2-Oxo-2-[(1R,3S,5R)-3-(3- phenyl-cyclohexylcarbamoyl)-2- aza-bicyclo[3.1.0]hex-2-yl]-ethyl}- 1H-pyrazolo[3,4-c]pyridine-3- carboxylic acid amideDia 2::US9815819, 82

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC2CCCC(C2)c2ccccc2)c2cnccc12

InChI Key InChIKey=KTCYDLCEZQOKFV-IRCYLWAESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355717   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM355717(1-{2-Oxo-2-[(1R,3S,5R)-3-(3- phenyl-cyclohexylcarb...)
Affinity DataIC50:  230nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent