BDBM355906 1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-6-yl)-3- (3,5-dichloro-4-(2H- 1,2,3-triazol-2- yl)phenyl)urea::US10442808, Example 30::US9815842, Example 30

SMILES CC(C)c1c(NC(=O)Nc2cc(Cl)c(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=BTCRBXDLFHVOCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355906   

LigandPNGBDBM355906(1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-...)
Affinity DataIC50:  0.00300nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM355906(1-(2-chloro-7- isopropylpyrazolo[1, 5-a]pyrimidin-...)
Affinity DataIC50:  0.00300nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent