BDBM355948 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- methyl-7-(1- methylcyclopropyl) pyrazolo[1,5- a]pyrimidin-6-yl)urea::US10442808, Example 72::US9815842, Example 72
SMILES Cc1cc2ncc(NC(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c(n2n1)C1(C)CC1
InChI Key InChIKey=BQEHSGWEEHOZPD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355948
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00300nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00300nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair