BDBM356129 US9815846, Compound 129

SMILES Cn1ccc(-c2cc(C(=O)Nc3cnc(Cc4nnc[nH]4)nc3-c3ccccc3)c(F)cc2C(F)(F)F)n1

InChI Key InChIKey=MDGKFZLEMPAIIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356129   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 356129BDBM356129(US9815846, Compound 129)
Affinity DataIC50: 0.25nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent