BDBM356705 1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- isopropylimid azolidin-2-one::US10214507, Compound 98::US10759777, Compound 98

SMILES CC(C)N1CCN(CC(O)Cn2c3ccccc3c3ccccc23)C1=O

InChI Key InChIKey=DBPNDSFSOWWTKO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356705   

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356705(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- isop...)
Affinity DataEC50:  269nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356705(1-(3-(9H-carbazol- 9-yl)-2- hydroxypropyl)-3- isop...)
Affinity DataEC50:  269nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent