BDBM35672 benzazepinelidene acetamide derivative, 1g

SMILES C[C@H]1CCN(C1)c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(=O)NCCO)c3ccccc23)c(c1)C(F)(F)F

InChI Key InChIKey=WACXYFAARRFXRL-SZHLLGMXSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35672   

TargetVasopressin V2 receptor(Human)
Astellas Pharma

LigandPNGBDBM35672(benzazepinelidene acetamide derivative, 1g)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/molepH: 7.4 T: 23°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVasopressin V1a receptor(Human)
Astellas Pharma

LigandPNGBDBM35672(benzazepinelidene acetamide derivative, 1g)
Affinity DataKi:  43nM ΔG°:  -9.98kcal/molepH: 7.4 T: 23°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed