BDBM356724 (1R,4S)-2-((R)-3- (9H-carbazol-9-yl)- 2-hydroxypropyl)- 2-azabi- cyclo[2.2.1]heptan- 3-one::US10214507, Compound 107::US10759777, Compound 107

SMILES O[C@@H](CN1[C@@H]2CC[C@@H](C2)C1=O)Cn1c2ccccc2c2ccccc12

InChI Key InChIKey=JYEKVRNBZSYHLZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356724   

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356724((1R,4S)-2-((R)-3- (9H-carbazol-9-yl)- 2-hydroxypro...)
Affinity DataEC50:  89nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356724((1R,4S)-2-((R)-3- (9H-carbazol-9-yl)- 2-hydroxypro...)
Affinity DataEC50:  89nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent