BDBM356928 (R)-1-(3-(3,6- difluoro-9H- carbazol-9-yl)-2- hydroxypropyl)imid- azolidin-2-one::US10214507, Compound 114::US10759777, Compound 114

SMILES c1cc2c(cc1F)c3cc(ccc3n2C[C@H](CN4CCNC4=O)O)F

InChI Key InChIKey=MUVYYQQLOKRDQS-UHFFFAOYSA-N

Data  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356928   

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356928((R)-1-(3-(3,6- difluoro-9H- carbazol-9-yl)-2- hydr...)
Affinity DataEC50:  287nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetPeriod circadian protein homolog 2(Human)
Reset Therapeutics

US Patent
LigandPNGBDBM356928((R)-1-(3-(3,6- difluoro-9H- carbazol-9-yl)-2- hydr...)
Affinity DataEC50:  287nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent