BDBM357006 5-Amino-3-ethyl-1-(3-fluoro-2-methylphenyl)-N-[5-trifluoromethyl-2-pyridyl]pyrazole-4-carboxamide::US10214509, Example 143

SMILES CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1cccc(F)c1C

InChI Key InChIKey=UWLSZMSRUXKANW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357006   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM357006(5-Amino-3-ethyl-1-(3-fluoro-2-methylphenyl)-N-[5-t...)
Affinity DataIC50:  1.00E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM357006(5-Amino-3-ethyl-1-(3-fluoro-2-methylphenyl)-N-[5-t...)
Affinity DataIC50:  300nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent