BDBM357011 5-Amino-1-(3-fluoro-2-methylphenyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-1H-imidazole-4-carboxamide::US10214509, Example 251

SMILES Cc1c(F)cccc1-n1cnc(C(=O)Nc2ccc(cn2)C(F)(F)F)c1N

InChI Key InChIKey=KOSCLEJPOZWNNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357011   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM357011(5-Amino-1-(3-fluoro-2-methylphenyl)-N-(5-(trifluor...)
Affinity DataIC50:  200nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent