BDBM357075 5-(5-chloro-2-(1h-tetrazol-1-yl)phenyl)-2-(15-fluoro-24-((methoxycarbonyl)amino)-4-oxo-3-aza-1(1,3),2(1,2) -dinenzenacyclononaphane-9-yl)pyridine 1-oxide::US10214512, Example 52

SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCCC(c3cc(F)cc-2c3)c2ccc(c[n+]2[O-])-c2cc(Cl)ccc2-n2cnnn2)c1

InChI Key InChIKey=DJNMZGYTLZEVCG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357075   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357075(5-(5-chloro-2-(1h-tetrazol-1-yl)phenyl)-2-(15-fluo...)
Affinity DataKi:  0.320nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetKallikrein-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357075(5-(5-chloro-2-(1h-tetrazol-1-yl)phenyl)-2-(15-fluo...)
Affinity DataKi:  1.43nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent