BDBM357230 5-(5-chloro-2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)phenyl)-2-(11-(difluoromethyl)-8-oxo-11H-9-aza-1(5,4)-pyrazola-2(1,3) -benzenacyclononaphane-3-Yl)pyridine 1-oxide::US10214512, Example 165

SMILES [O-][n+]1cc(ccc1C1CCCCC(=O)Nc2cnn(C(F)F)c2-c2cccc1c2)-c1cc(Cl)ccc1-n1cc(nn1)C(F)(F)F

InChI Key InChIKey=OZMXFCXWDYBGGS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357230   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357230(5-(5-chloro-2-(4-(trifluoromethyl)-1H-1,2,3-triazo...)
Affinity DataKi:  0.210nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetKallikrein-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM357230(5-(5-chloro-2-(4-(trifluoromethyl)-1H-1,2,3-triazo...)
Affinity DataKi:  5.76nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent