BDBM357273 2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-3,4- diphenyl-1H-pyrazol-1- yl)methyl)cyclohexyl) methoxy)acetic acid::US10214518, Compound 146

SMILES OCCSc1c(c(nn1C[C@@H]1CC[C@H](COCC(O)=O)CC1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=GLAMVSLFXKZMDJ-OYRHEFFESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357273   

TargetMajor prion protein(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357273(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-3,4- diphe...)
Affinity DataIC50:  70nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent