BDBM357398 US10214519, Example 124

SMILES Cc1ccc(F)c2c(-n3c(C)nc4c(-c5nnc[nH]5)cc(N5CCOCC5)cc43)ccnc12

InChI Key InChIKey=DVWOZUUPOLUZMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357398   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 357398BDBM357398(US10214519, Example 124)
Affinity DataIC50: 9nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent