BDBM35742 sulfonamide deriv., 8

SMILES NS(=O)(=O)c1nnc(NC(=O)Cc2ccccc2)s1

InChI Key InChIKey=PQGMZYDYQJPUJM-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 35742   

TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  6.10nM ΔG°:  -11.2kcal/moleT: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  6.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  8.40nM ΔG°:  -11.0kcal/moleT: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  51nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  51nM ΔG°:  -9.94kcal/moleT: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35742(sulfonamide deriv., 8)
Affinity DataKi:  63nM ΔG°:  -9.82kcal/molepH: 7.4 T: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed