BDBM357551 US10214519, Example 307

SMILES Fc1ccc(Cl)c2nccc(-n3c(nc4c(cc(cc34)N3CCOCC3)-c3cnc(Cl)[nH]3)C3CC3)c12

InChI Key InChIKey=ACYOAIKBJXDKPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357551   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM357551(US10214519, Example 307)
Affinity DataIC50:  8nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent