BDBM357626 US10214519, Example 392

SMILES Cc1nc2c(-c3nnc[nH]3)cc(N3CCOCC3)cc2n1-c1c(-c2nnc[nH]2)cnc2ccccc12

InChI Key InChIKey=DJKQLJQOOYNLRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357626   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 357626BDBM357626(US10214519, Example 392)
Affinity DataIC50: 9nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent