BDBM357700 N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7′-oxo-6′,7′-dihydro-5′H-spiro[cyclopropane-1,8′-pyrido[4,3-d]pyrimidine]-2′-yl)methyl)acrylamide::US10214528, Example 4::US10738048, Example 4::US11014923, Example 4::US11667635, Example 4::US9890156, Example 4

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)nc3C3(CC3)C2=O)c1F

InChI Key InChIKey=CHMUDVGOMLARII-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 357700   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357700(N-((6′-(2,6-difluoro-3,5-dimethoxyphenyl)-7&...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent