BDBM357705 N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-difluorocyclobutyl)-2-oxo-1,2,3,4-tetrahydropyrido[4,3-d]pyrimidin-7-yl)methyl)acrylamide::US10214528, Example 9::US10738048, Example 9::US11014923, Example 9::US11667635, Example 9::US9890156, Example 9

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)cc3N(C3CC(F)(F)C3)C2=O)c1F

InChI Key InChIKey=QIUUMEUBLDQMON-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 357705   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM357705(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3,3-di...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent