BDBM357712 N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluorobenzyl)-2-oxo-1,2,3,4-tetrahydropyrido[4,3-d]pyrimidin-7-yl)methyl)acrylamide::US10214528, Example 16::US10738048, Example 16::US11014923, Example 16::US11667635, Example 16::US9890156, Example 16

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)cc3N(Cc3cccc(F)c3)C2=O)c1F

InChI Key InChIKey=DQQVACSMEANERY-UHFFFAOYSA-N

Data  20 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 357712   

TargetFibroblast growth factor receptor 1(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:TBDMore data for this Ligand-Target Pair

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TargetFibroblast growth factor receptor 4(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

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TargetFibroblast growth factor receptor 3(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:TBDMore data for this Ligand-Target Pair

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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair

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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  125nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetFibroblast growth factor receptor 2(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  125nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  125nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetFibroblast growth factor receptor 4(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand InfoPC cidPC sid

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TargetFibroblast growth factor receptor 2(Human)
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US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails US Patent

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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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Ligand InfoPC cidPC sid

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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
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Ligand InfoPC cidPC sid

In DepthDetails US Patent

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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand InfoPC cidPC sid

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TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand InfoPC cidPC sid

In DepthDetails US Patent

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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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Ligand InfoPC cidPC sid

In DepthDetails US Patent

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TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent

LigandBDBM357712(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(3-fluo...)Copy SMILESCopy InChI

Affinity DataIC50:  115nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

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