BDBM357758 KM-05-100/(I-11)::US10214530, Example 11

SMILES Cn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ccc(Br)cc3[nH]1)n2Cc1ccccc1

InChI Key InChIKey=YAWZRUWHTCJPCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357758   

TargetTryptophan 5-hydroxylase 2(Human)
Max Delbruck Center

US Patent
LigandChemical structure of BindingDB Monomer ID 357758BDBM357758(KM-05-100/(I-11) | US10214530, Example 11)
Affinity DataIC50: 740nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max Delbruck Center

US Patent
LigandChemical structure of BindingDB Monomer ID 357758BDBM357758(KM-05-100/(I-11) | US10214530, Example 11)
Affinity DataIC50: 4.14E+3nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent