BDBM357771 KM-05-180/(I-208)::US10214530, Example 26

SMILES CCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ncccc3[nH]1)n2Cc1ccccc1

InChI Key InChIKey=CIFNDBGCNHPCBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357771   

TargetTryptophan 5-hydroxylase 2(Human)
Max Delbruck Center

US Patent
LigandChemical structure of BindingDB Monomer ID 357771BDBM357771(KM-05-180/(I-208) | US10214530, Example 26)
Affinity DataIC50: 850nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Max Delbruck Center

US Patent
LigandChemical structure of BindingDB Monomer ID 357771BDBM357771(KM-05-180/(I-208) | US10214530, Example 26)
Affinity DataIC50: 2.08E+4nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent