BDBM357860 US10214536, Compound 11

SMILES Nc1nc2oc3ccc(cc3c(=O)c2cc1C(O)=O)C1CCCC1

InChI Key InChIKey=IFNUUMBKQALSBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 357860   

TargetSerine/threonine-protein kinase TBK1(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM357860(US10214536, Compound 11)
Affinity DataIC50:  340nMAssay Description:Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM357860(US10214536, Compound 11)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase TBK1(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM357860(US10214536, Compound 11)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed