BDBM35788 pyrimidine-4-carboxamide, 57

SMILES Nc1nc(cc(n1)-c1ccccc1)C(=O)NCc1ccccn1

InChI Key InChIKey=JEPXTONICDQEJX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35788   

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

LigandPNGBDBM35788(pyrimidine-4-carboxamide, 57)
Affinity DataKi:  14nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

LigandPNGBDBM35788(pyrimidine-4-carboxamide, 57)
Affinity DataKi:  66nM ΔG°:  -9.66kcal/molepH: 7.5 T: 21°CAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed