BDBM35790 pyrimidine-4-carboxamide, 61

SMILES Nc1nc(cc(n1)-c1cccc(F)c1)C(=O)NCc1ccccn1

InChI Key InChIKey=KFWWKUUBQRSFND-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35790   

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

LigandPNGBDBM35790(pyrimidine-4-carboxamide, 61)
Affinity DataKi:  18nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

LigandPNGBDBM35790(pyrimidine-4-carboxamide, 61)
Affinity DataKi:  38nM ΔG°:  -9.98kcal/molepH: 7.5 T: 21°CAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed