BDBM359806 US9822103, Example 66::rac-(3aS,8bS) N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(6-methoxypyridin-3-yl)-3a-methyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-7-carboxamide

SMILES COc1ccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc3c2O[C@@]2(C)CCC[C@@H]32)cn1

InChI Key InChIKey=QEVPJQFECBSBPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359806   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 359806BDBM359806(rac-(3aS,8bS) N-((4,6-Dimethyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50: 750nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent