BDBM359809 US9822103, Example 69::rac-(3aS,8bS)-5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3a,6-dimethyl-2, 3,3a, 8b-tetrahydro-1H-cyclopenta[b]benzofuran-7-carboxamide

SMILES Cc1cc(C)c(CNC(=O)c2cc3c(c(Br)c2C)O[C@@]2(C)CCC[C@@H]32)c(=O)[nH]1

InChI Key InChIKey=FCMMYTPNRISTRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359809   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 359809BDBM359809(rac-(3aS,8bS)-5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-d...)
Affinity DataIC50: 500nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent