BDBM359875 US9822120, Compound 31

SMILES CC(=O)N1CCC(CC1)c1nc(-c2ccc(Oc3cc(F)cc(OCc4cnc(C)nc4)c3)cc2)c2c(N)nccn12

InChI Key InChIKey=ADNLTCJFYJOAKH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359875   

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359875(US9822120, Compound 31)
Affinity DataEC50: <100nMAssay Description:Method B: hBTK kinase is diluted in buffer and all compounds were prepared to 50× final assay concentration in 100% DMSO. This working stock of the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Pharmascience

US Patent
LigandPNGBDBM359875(US9822120, Compound 31)
Affinity DataEC50: <100nMAssay Description:Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent