BDBM360434 US9828369, Example 7::methyl 3-(8-((3-(tert-butyl)-1-methyl- 1H-pyrazole-5-carboxamido)methyl) isoquinolin-5-yl)benzoate

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2cc(nn2C)C(C)(C)C)c2cnccc12

InChI Key InChIKey=AMGFTJVGHGTGKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360434   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360434(methyl 3-(8-((3-(tert-butyl)-1-methyl- 1H-pyrazole...)
Affinity DataIC50: 111nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent