BDBM360439 8-((isoquinoline-5- carboxamido)methyl)-5-(3- (methoxycarbonyl)phenyl) isoquinolin-2-ium::US9828369, Example 12

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2cccc3cnccc23)c2cnccc12

InChI Key InChIKey=IPRXTNMJWSEELW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360439   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360439(8-((isoquinoline-5- carboxamido)methyl)-5-(3- (me...)
Affinity DataIC50: 196nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent