BDBM360930 4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxypiperidin- 4-yl)methyl)- 3-(1H- tetrazol-5-yl) benzene-1,2- disulfonamide::US10221163, Example 86::US10544130, Example 86

SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)NCC1(O)CCNCC1

InChI Key InChIKey=LHGHDVNQBZMSRJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 360930   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.129nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.0270nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.0760nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.129nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.0270nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360930(4-(2- aminobenzo [d]thiazol- 4-yl)-N1-((4- hydroxy...)
Affinity DataIC50:  0.0760nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent