BDBM360941 3-(4-(2-amino- benzo[d]thiazol- 4-yl)-2-sulfamoyl-3- (1H-tetrazol-5-yl) phenylsulfonamido) quinuclidin- 1-ium 2,2,2- trifluoroacetate::US10221163, Example 97::US10544130, Example 97

SMILES Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)NC1CN2CCC1CC2

InChI Key InChIKey=XHSAXLCYFREUHS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 360941   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.0210nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.0210nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.222nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.222nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.383nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360941(US10221163, Example 97 | 3-(4-(2-amino- benzo[d]th...)
Affinity DataIC50: 0.383nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent