BDBM361109 (R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- aminobutan-2-yl)-3-(2H- tetrazol-5-yl)benzene-1,2- disulfonamide::US10221163, Example 266::US10544130, Example 266

SMILES C[C@H](CCN)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=TZBMGYRGFPKTLT-HNLKAFMCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361109   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.477nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.0280nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.115nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.477nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.0280nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361109((R)-4-(2-amino-1H- benzo[d]imidazol-4-yl)-N1-(4- a...)
Affinity DataIC50:  0.115nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent