BDBM362042 (S)-3-(2-(cyclopropyl((2,6-diamino-5-cyanopyrimidin-4-yl)amino)methyl)-5-(difluoromethyl)-4-oxoquinazolin-3(4H)-yl)benzamide::US10221197, Compound 35
SMILES C[C@H](Nc1nc(N)nc(N)c1Cl)c1nc2c(cccc2c(=O)n1-c1cccc(c1)C(N)=O)C#N
InChI Key InChIKey=JRBRZMMWMSBLET-JTQLQIEISA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 362042
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent