BDBM362052 (S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)amino)ethyl)-5-bromo-4-oxoquinazolin-3(4H)-yl)phenyl)-3-ethylurea::US10221197, Compound 45
SMILES CCNC(=O)Nc1cccc(c1)-n1c(nc2cccc(CC=C)c2c1=O)[C@H](C)Nc1ncnc(N)c1C#N
InChI Key InChIKey=AJVXVERLHNHUKG-INIZCTEOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 362052
Affinity DataIC50: 6.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
US Patent