BDBM362052 (S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)amino)ethyl)-5-bromo-4-oxoquinazolin-3(4H)-yl)phenyl)-3-ethylurea::US10221197, Compound 45

SMILES CCNC(=O)Nc1cccc(c1)-n1c(nc2cccc(CC=C)c2c1=O)[C@H](C)Nc1ncnc(N)c1C#N

InChI Key InChIKey=AJVXVERLHNHUKG-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362052   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM362052((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50:  6.00E+3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM362052((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50:  1.80E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM362052((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent