BDBM363023 Methyl 6-((6-chloro-7-fluoro-1-(2-(indolin-1-yl)-2-oxoethyl)-2-methyl-1H-indol-3-yl)thio)picolinate ::US9850203, Compound 2-3

SMILES Cc1c(Sc2cccc(n2)C(O)=O)c2ccc(Cl)c(F)c2n1CC(=O)N1CCc2ccccc12

InChI Key InChIKey=LUSJGRSLCVMTIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363023   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM363023(US9850203, Compound 2-3 | Methyl 6-((6-chloro-7-fl...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent