BDBM363047 3-[6-Chloro-7-fluoro-1-[2-(5′-fluorospiro[cyclopropane-1,3′-indoline]-1′-yl)-2-oxo-ethyl]-2-methyl-indol-3-yl]sulfanyl-2-fluoro-benzoic acid ::US9850203, Compound 3-23

SMILES Cc1c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c2n1CC(=O)N1CC2(CC2)c2cc(F)ccc12

InChI Key InChIKey=HZEOMKPCWCPTLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363047   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM363047(US9850203, Compound 3-23 | 3-[6-Chloro-7-fluoro-1-...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent