BDBM363052 3-((6-chloro-2-cyclopropyl-7-fluoro-1-(2-(indolin-1-yl)-2-oxoethyl)-1H-indol-3-yl)thio)-2-fluorobenzoate::US9850203, Compound 4-29

SMILES [O-]C(=O)c1cccc(Sc2c(C3CC3)n(CC(=O)N3CCc4ccccc34)c3c(F)c(Cl)ccc23)c1F

InChI Key InChIKey=XPGYRIFMQSKLGO-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363052   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM363052(US9850203, Compound 4-29 | 3-((6-chloro-2-cyclopro...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent