BDBM363060 3-((2,6-dichloro-7-fluoro-1-(2-(3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl)-2-oxoethyl)-1H-indol-3-yl)thio)-2-fluorobenzoate::US9850203, Compound 5-5

SMILES OC1(CCN(C1)C(=O)Cn1c(Cl)c(Sc2cccc(C([O-])=O)c2F)c2ccc(Cl)c(F)c12)C(F)(F)F

InChI Key InChIKey=YHAOLUSBDAZQKI-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363060   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandPNGBDBM363060(US9850203, Compound 5-5 | 3-((2,6-dichloro-7-fluor...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent