BDBM363794 2-Ethyl-6,7-dimethoxy-N-(4-methylbenzyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide::US9856220, Example 153::US9856220, Example 161

SMILES CCn1cc(C(=O)NCc2ccc(C)cc2)c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=HKERMEHDLDDAGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363794   

LigandPNGBDBM363794(US9856220, Example 153 | US9856220, Example 161 | ...)
Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandPNGBDBM363794(US9856220, Example 153 | US9856220, Example 161 | ...)
Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent