BDBM363817 2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoline-4-carboxylic acid cyclohexylmethyl-amide::US9856220, Example 190

SMILES CCC(CC)n1cc(C(=O)NCC2CCCCC2)c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=ASFLDKXYCIQNHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363817   

LigandPNGBDBM363817(US9856220, Example 190 | 2-(1-Ethyl-propyl)-6,7-di...)
Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent