BDBM363837 6,7-Dimethoxy-N-((5-methylthiophen-2-yl)methyl)-1-oxo-2-(pentan-3-yl)-1,2-dihydroisoquinoline-4-carboxamide::US9856220, Example 237
SMILES CCC(CC)n1cc(C(=O)NCc2ccc(C)s2)c2cc(OC)c(OC)cc2c1=O
InChI Key InChIKey=BSAAOPMHCXYQBC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 363837
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie Deutschland
US Patent
Abbvie Deutschland
US Patent
Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair