BDBM363844 (S)-N-(1-(4-fluorophenyl)ethyl)-6,7-dimethoxy-1-oxo-2-(pentan-3-yl)-1,2-dihydroisoquinoline-4-carboxamide::US9856220, Example 246

SMILES CCC(CC)n1cc(C(=O)N[C@@H](C)c2ccc(F)cc2)c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=MLVOPIUUBQPQGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363844   

LigandPNGBDBM363844(US9856220, Example 246 | (S)-N-(1-(4-fluorophenyl)...)
Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent