BDBM363886 2-Ethyl-6,7-dimethoxy-N-[(4-methyl-2-thienyl)methyl]-1-oxo-isoquinoline-4-carboxamide::US9856220, Example 317

SMILES CCn1cc(C(=O)NCc2cc(C)cs2)c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=OCHGEBROIUMZNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363886   

LigandPNGBDBM363886(US9856220, Example 317 | 2-Ethyl-6,7-dimethoxy-N-[...)
Affinity DataIC50: 150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent