BDBM364324 US10570156, Compound 6::US9856274, Compound 6

SMILES Cc1cnc(c2n1nc(n2)CCc3nc4c5cccnc5ccc4n3C)C

InChI Key InChIKey=BHYRFKDBQRBVEU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 364324   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM364324(US9856274, Compound 6 | US10570156, Compound 6)
Affinity DataIC50: 10nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM364324(US9856274, Compound 6 | US10570156, Compound 6)
Affinity DataIC50: 10nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent