BDBM364389 US10913711, Compound 2t::US11555013, Compound 2t::US9862679, Compound 2t

SMILES CCCCNC(=O)CSC(c1ccc(Br)cc1)c1ccc(Br)cc1

InChI Key InChIKey=PZLJZRXGHIMLHP-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 364389   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  722nMAssay Description:Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  729nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  729nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  729nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.09E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.09E+3nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain SERT after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.09E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.09E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.60E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetTransporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.60E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetTransporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandChemical structure of BindingDB Monomer ID 364389BDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.60E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent